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The Syndicate Blog

Cleanroom ISO certification and new batch's on the way

By TKS 11 days ago 152 Views 1 comment

We are working hard to get caught up and new batch's are in progress. The team has worked 8 weeks straight 7 days a week to keep up with orders and finish the cleanroom. We have applied to be a AKA approved vendor and it is in progress. We have an ISO certification scheduled which our main room will be an ISO 7 and gowning, quarantine ISO 8. 

Manufacturing supplements does not require a certified ISO rating just a "cleanroom" with industry standards. We wanted to take it a step further and built ours to be able to show and document to our customers it has been inspected and certified by a 3rd party. Customer safety and our transparency to show our customers we are truly serious about being a leading vendor in this industry.  

ISO Classifications are 1-8. They are a critical factor in cleanroom design.

An important design feature is controlling air-change per hour (ACH), also known as the air-change rate, or ACR. This refers to the number of times each hour that filtered outside air replaces the existing volume in a building or chamber. In a normal home, an air-conditioner changes room air 0.5 to 2 times per hour. In a cleanroom, depending on classification and usage, air change occurs anywhere from 10 to more than 600 times an hour.

Achieving the optimal air change rate requires proper ceiling
fan coverage. The cleanest modular cleanroom
incorporates filter/fan units (FFUs) in every 2’ x 4’ (610 mm x 1219 mm) ceiling bay. This near-100% coverage provides a laminar flow of filtered air to quickly remove contaminants from the room, thus meeting FS209E standards for Class 10 and ISO Class 1 standards.

Our cleanroom is positive pressure.

What is positive pressure?

Positive Pressure Cleanrooms are designed to maintain positive pressure, preventing "unclean" (contaminated) air from flowing inside and less-clean air from flowing into clean areas. The idea is to ensure that filtered air always flows from cleanest to less-clean spaces. So inside the cleanroom air flow is restricted to just a few small vents. Only purified air is introduced from special Hepa filters that are 99.9999% rated.

An ISO 7, 15-25% of the ceiling is filter units. 

Contact sufaces and equipment are all stainless steel making them easy to clean and they won't support bacteria growth. We also do random microbial testing on contact surfaces. 

 

Kratom Consumer Protection Act being adopted

By Blogger W 17 days ago 30 Views No comments

Utah has passed the Kratom consumer protection act. You can see the details in the below link. This is a step toward Kratom consumer safety and just common sense. https://le.utah.gov/~2019/bills/static/SB0058.html

Georgia just passed there own version. 

Sponsored by Representatives Hill, Caldwell, Jones, Mathiak, and Newton, the Georgia version of the Kratom Consumer Protection Act does the following:

  • Restricts kratom sales to kids under the age of 18
  • Requires clear labeling of kratom products labels that shows:
    • The amount of mitragynine and 7-hydroxymitragynine in the product
    • A list of each ingredient listed in order of predominance
    • Clear directions for use
    • Precautionary statements on the safety and effectiveness of the product
    • The name and address of the manufacturer

 

It's great to see progress being made to clear out the bad actors and protect comsumers. Hopefully more states will follow and the FDA will look at the science and the vendors in the industry will rapidly adopt cGMP standards.  

 

Virtual Gift Cards are here!

By TKS 2 months ago 207 Views No comments

GIFT CARDS

magento gift card extension

 

CUSTOMIZABLE GIFT CARD

 configure gift cards according to your needs. Before adding the certificate to cart visitors can:

  • Choose the certificate value or specify their own custom value;
  • Choose the card image;
  • Write a gift message;
  • Specify sender (YOU) and recipient data (YOU or a Friend);

All specified gift card details will be automatically displayed on the shopping cart page.

 

 

magento gift cart extension

GIFT CARD BALANCE

As soon as a gift voucher recipient gets a gift code via email and inserts it in a special gift card field, the card balance will be available on a customer account page in the Gift Card tab.

Gift card holders will be able to:

  • Add an unlimited number of gift codes;
  • Remove already used certificates;
  • See the current gift card balance;
  • See the certificate expiration date;
 

 

magento gift certificate extension

APPLY GIFT CODE ON THE SHOPPING CART PAGE

To apply an active gift card code on the shopping cart page customers just need to insert the code in a special field and click on the 'Add gift card' link below. Once the code is applied the new grand total price will be automatically recalculated and displayed.

On the shopping cart page gift card holders can:

  • Apply gift card code;
  • Check gift card status;
  • See gift card balance and expiration date;
 
 
 
CHECK OUT THE GIFT HERE

https://thekratomsyndicate.com/tks-gift-card.html

Our Loyalty Program

By TKS 2 months ago 898 Views No comments
The Loyalty program can be found in your account details. It is based on your purchase history and how much you have spent.

Processing Kratom #kratom

By TKS 2 months ago 363 Views No comments
Here we show our fresh picked mature kratom leaves being dried in Indonesia. This is our TKS Green being layed out on racks to begin drying. Once dried it will be crushed and de-stemed and then ground into a fine powder.

Welcome to the NEW website

By TKS 3 months ago 236 Views No comments
We just opened the new site here with alot of new features. Checkout your account page for details on the loyalty program that has replaced the old rewards program. It is based on a amount purchased and you will receive a discount % in checkout for everything on the site! We will be monitoring the site the next week and make small updates as needed to get it dialed in. Credit card processing will be in checkout very soon as we had to move the site over first before integrating the api in the shopping cart. This is just one of the first steps in alot of changes to come, stay tuned and subscribe to our newsletter, thank you!

My Thoughts on Kratom

By Admin 4 months ago 345 Views No comments

 

Dr. Yasir Bari

Monday, December 10, 2018

It hasn’t been long since humans have discovered that their very own invention, the allopathic medicine has failed them enough to damage the health in terms of morbidity and mortality via side effects of the harmful and synthetic ingredients found in those medications; that they are now turning to the Mother Nature again. Herbal medicines are once again are being studied in depth and with every passing day new researches are being published on the natural remedies. So one of the nature’s gifts we are discussing today is the magic herb called the Kratom or also known as Biak, Ketum, Kakuam, Ithang and Thom.

Kratom has been in use in the south East Asian countries like Thailand and Indonesia since centuries as a part of their traditional medicine for the treatment of aliments like opioid withdrawal, diarrhea and as a pain killer. Furthermore, it has also been used to increase energy, stamina, and limit fatigue and as a concentration booster. Since its active ingredients were discovered by the scientists Kratom made it’s well established place in the market as an alternative to many allopathic medicines to treat the problems mentioned above. The leaves of Kratom are consumed either by chewing, or by drying and smoking, putting into capsules, tablets or extract, or by boiling into a tea.

Kratom consumption is primarily motivated by its perceived effects that enhance well-being, occupational performance, and social interactions depending on an individual, as well as serving as a natural “home remedy” that is preferred by millions of Americans to conventional medicines. Like everything else, when used in quantities more than the prescribed usual doses it may produce some undesirable effects like nausea, vomiting dryness of mouth and headaches along with some irritability following the next dosage due to perceived dependence on the drug. This was something which was used as leverage against the consumption of the herb as an alternative medicine by the opponents of Kratom, well that we all know who could be; all the big pharmaceuticals who feared that the growing trend of its use may give strong competition to their harmful and addictive NSAIDs and Opioid derivative.

It doesn’t just stop at opposing the use, they somehow managed to do successful lobbying at the state levels, of course due to the hefty budgets at their back supporting their ambitions to pursue FDA and other drug regulating authorities to issue scheduling on the use of Kratom. Not only that, they were also successful to launch campaigns against its use as an addictive and illicit drug. Even the states where cannabis is now legal have banned the use of Kratom.

When we dig deeper into the actual realities and upon studying the reports issued by the scientists, submitted to FDA and other agencies, some of them were made public as well, it became evident that there were undoubted misunderstandings and meticulous ambitions behind all the negative publicity of the herb. As reported by the Washington Post in December 2016, Jack Henningfield, an addiction specialist from Johns Hopkins University and Vice President, Research, Health Policy, and Abuse Liability at Pinney Associates, issued a 127 page report which was developed to determine the appropriateness of CSA scheduling of kratom and/or its alkaloids and derivative products, and if so, the most appropriate schedule for kratom.

It was concluded by the study that kratom’s potential for abuse, tolerance, and dependence is lower than that of many schedule IV and V drugs and is well within the range of many nonscheduled drugs and substances (e.g., caffeine, nasal nicotine spray, fluoxetine, bupropion, and dextromethorphan). Although kratom and its primary alkaloids MG and 7-OH-MG share certain characteristics with controlled substances, as do many nonscheduled substances, there does not appear to be a public health risk that would warrant control of kratom products or their alkaloids under the CSA. It was suggested that Kratom should be regulated as a natural supplement, such as St. Johns Wort or Valerian, under the FDA's Food, Drug and Cosmetic Act.

Furthermore, people who were actually using kratom and were benefiting from its useful effects it was just like an lifesaving drug for them, relieving them from the suffering of chronic pain or helping people overcome their opioid withdrawals and that numbers in hundreds of thousands are likely to be adversely affected and possibly motivated to seek illicit sources if lawfully marketed kratom were no longer available.

Placing kratom into schedule is just like placing it in the same category as heroin, LSD or marijuana, and prevent access for medical research, a concern for many experts, consumers, and advocacy groups. Lack of quality scientific evidence confounds the evaluation of the safety of kratom. So it would be much more effective if the FDA and other agencies first fund the proper research on the product up to the level of their satisfaction and in line with the health standards before completely banning and lifting it from the market.

8 factor analysis of kratom

By Admin 5 months ago 1314 Views No comments

The purpose of this document is to review the data related to the abuse potential and toxicity of Mitragyna speciosa (also known as kratom) and its primary alkaloids, mitragynine (MG) and 7-hydroxy-mitragynine (7-OH-MG), and the relevance of those data to the doses found in kratom.


We do not recommend scheduling of kratom or any of its specific alkaloids under the Controlled Substances Act. Kratom has a low potential for abuse and a low dependence liability and there is insufficient evidence of personal harm, adverse health effects or detriment to the public health to warrant control under the CSA.

Effectively banning the availability of kratom through scheduling could precipitate public health problems that do not presently exist or are at very low levels, because this would shift the market place from a largely lawful retail market to illicit manufacturers and distributors with no regulated labeling, purity or content standards, or effective ability to remove adulterated products from the market. Appropriate regulation of kratom under the FDCA is the most effective way to protect the public health by ensuring appropriate access and oversight and to sustain the overall very low adverse personal and public health effects associated with kratom consumption.

Full analysis can be found here

http://216.30.191.148/HL-AKA-Eight_Factor_and_Recommendations_by_PinneyAssoc.pdf

Tumeric and it's health benefits

By System Administrator 5 months ago 120 Views No comments

Turmeric is the spice that gives curry its yellow color.

It has been used in India for thousands of years as a spice and medicinal herb.

Recently, science has started to back up what Indians have known for a long time — it really does contain compounds with medicinal properties (1).

These compounds are called curcuminoids, the most important of which is curcumin.

Curcumin is the main active ingredient in turmeric. It has powerful anti-inflammatory effects and is a very strong antioxidant.

However, the curcumin content of turmeric is not that high. It’s around 3%, by weight (2).

Most of the studies on this herb are using turmeric extracts that contain mostly curcumin itself, with dosages usually exceeding 1 gram per day.

It would be very difficult to reach these levels just using the turmeric spice in your foods.

Therefore, if you want to experience the full effects, you need to take a supplement that contains significant amounts of curcumin.

Unfortunately, curcumin is poorly absorbed into the bloodstream. It helps to consume black pepper with it, which contains piperine, a natural substance that enhances the absorption of curcumin by 2,000% (3).

The best curcumin supplements contain piperine, substantially increasing their effectiveness.

Curcumin is also fat soluble, so it may be a good idea to take it with a fatty meal.

What is CBD?

By System Administrator 5 months ago 235 Views 2 comments

What is CBD?

CBD comes from the Cannabis sativa plant, which is also used to produce hemp and marijuana. It’s extracted from the resin of cannabis buds and flowers and usually diluted with another oil, like MCT.

The major difference between CBD and marijuana is that it does not contain THC, the psychoactive compound that probably comes to mind when you think of marijuana. That means you won’t get high from using CBD.

How does CBD affect the body?

Marijuana and CBD work by acting on the body’s endocannabinoid system. This system’s main job is to maintain homeostasis and help the body adapt to outside stressors.

There are two main types of cannabinoids—endo (produced naturally within the body) and phyto (produced from a plant). CBD is one type of phytocannabinoid. Phytocannabinoids mimic endocannabinoids, so they can act like a supplement, giving you a boost beyond what your body can produce.

Receptors for cannabinoids are found in the digestive, reproductive, nervous, and immune systems. Because cannabinoids interact with almost every system in our bodies, they’re often touted as a cure-all. While they’re not truly able to heal everything, they do regulate neurotransmitter function, inflammation, mitochondrial function, and metabolism.

Who should try CBD oil?

CBD is safe for almost everyone, according to a recent report from the World Health Organization, but check with your doctor before starting any CBD product, especially if you are pregnant or on any medications. Research has shown several CBD oil benefits, ranging from alleviating social anxiety to improving rheumatoid arthritis.

CBD health benefits.

IMPROVES MOOD DISORDERS.

CBD works directly on the brain receptors 5HT1A (serotonin) and GABA (an inhibitory neurotransmitter). Lower levels of these can contribute to anxiety and depression.


LOWERS INFLAMMATION.

Suppresses cytokine production and induces T-regulatory cells to protect the body from attacking itself, which can help autoimmune conditions.

DECREASES CHRONIC PAIN.

Inhibits transmission of neuronal signalling through pain pathways.

AIDS GUT HEALTH.

Helps heal the leaky tight junctions that contribute to intestinal permeability and decreases spasmodic activity common in irritable bowel syndrome.

HELPS TREAT SEIZURES.

May relieve epilepsy in children.